Case studies in Serology and PCR testing: uses and limitations - Recording

Advances in molecular diagnostics and serological testing have transformed modern microbiology, enabling rapid and sensitive detection of infectious diseases. However, interpretation of these investigations remains highly dependent on clinical context, timing of sampling, and an understanding of each method’s limitations.

This interactive case-based lecture explored the practical applications of serology and PCR testing through real-world clinical microbiology scenarios. Participants examined how laboratory results can support and occasionally mislead clinical decision-making.

The session highlighted key principles including diagnostic stewardship, window periods, seroconversion, false-positive and false-negative results, prolonged nucleic acid detection. Emphasis was on integrating laboratory data with clinical assessment to optimise patient management.

Designed for microbiology and virology trainees, this lecture aimed to strengthen diagnostic reasoning and improve confidence in interpreting serological and molecular investigations in routine clinical practice.

 

Microbiology webinars for trainees

Following feedback from members, we are trying a new format for delivering training this year, replacing the in-person Microbiology training day at LabMedUK with free monthly webinars. The topics have been suggested by members and are delivered by senior clinical scientists and colleagues. In the final webinar of the year, trainees have the opportunity to present recent audits.