Battered brains, germs and genes: Tomorrow's POCT empowering enhanced healthcare

9.30am – 11am BST, 11 June 2025 ‐ 1 hour 30 mins

Parallel session

In this session, we’ll explore how point of care testing continues to revolutionise clinical decision-making, particularly in critical and high-acuity settings. We’ll cover a range of topics, branching out from traditional POCT disciplines, including MT-RNR1 gene testing in neonates with sepsis to detect susceptibility to aminoglycoside-induced ototoxicity, a crucial step in preventing hearing loss and later need for cochlear implants. We’ll also discuss how POCT can be used in the management of traumatic brain injury to reduce unnecessary CT scans, improving patient care, minimizing radiation exposure and reducing the burden on radiology departments. Additionally, we’ll look at the role of POC testing in urinary tract infections, and its vital contribution to antimicrobial stewardship, helping to optimize treatment at the first encounter and prevent overprescription. These advancements are setting new standards in healthcare, improving patient outcomes, and enhancing resource efficiency. We’re excited to share insights into these cutting-edge developments and their impact on clinical practice.

Chair:  Fiona Riddoch

9.30  Genetic POCT – Greater Manchester POCT network experience - Sharman Harris

10.00  AMS for urinary tract infections in the community; a role for point-of-care testing? Philip Turner
Acute uncomplicated urinary tract infections (UTI) are one of the commonest presentations in primary care settings. Around half of all women experience one or more episodes in their lifetimes and a quarter of all culture-positive infections are associated with resistant uropathogens. European estimates have shown that although approximately 30% of symptomatic primary care patients have a culturable infection, the majority receive antibiotics. Safe optimisation of antibiotic prescribing is a key element of AMS, however existing diagnostics for UTI accessible to acute care settings are insufficient to influence immediate decision making, being either too slow or adding minimal diagnostic value.

Recent years have witnessed the emergence of multiple novel point-of-care diagnostics for UTI, with assays of sufficient interest to motivate the publication of NICE Early Value Assessment HTE7 on this subject and with one candidate awarded the prestigious Longitude Prize on AMR. During this talk we will explore the role point-of-care tests for UTI might play in antimicrobial stewardship in community healthcare settings, with reference to the technologies under investigation within the plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN) study.

10.30  Traumatic brain injury POCT